Which disease, carried by European explorers and settlers, killed up to 50% of the Native American population?

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Which disease, carried by European explorers and settlers, killed up to 50% of the Native American population?

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There were many diseases spread that killed the Native American population when the Europeans settled, but the deadliest one was smallpox. Smallpox is what really triggered the Atlantic Slave Trade, because so many natives died that settlers lost their workforce.

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