The answer depends of the kind of non-randommating. If the non-random mating is the kind of positive assortative mating then it tends to increase the frequencies of homozygous genotypes. Positive assortative mating when individuals mate with other individuals like themselves. If the non-random mating is the kind of negative assortative mating, then the effect is the opposite as of the positive assortative mating, this is it tends to decrease the homozygous genotypes.
