Bulary Review: Dose-response Analysis Reset Help 1. The is the adverse effects an organism experiences when exposed to a toxic substance. dose 2. The amount of a toxic substance to which an organism is exposed is the response 3. Some toxic substances elicit effects only when they overwhelm the body's defenses above an) dose. LDS ED. threshold 4. One example of a(n) would be the quantity of a toxic substance that causes 50% of lab rats to show reduced appetite after exposure. 5. The organisms. is the quantity of a toxic substance needed to kill half of the study Cuba