in his work with pneumonia-causing bacteria and mice, Griffith worked with an S strain of the bacteria, which was lethal to the mice and an Rstrain, which was not lethal to the mice. Griffith found that: a. genetic information from Scells was transferred to cells, making them pathogenic b. heat-killed Scells were lethal to mice. c. the polysaccharide cost of the R bacteria was lethal in mice. d. the protein coat from Scells was able to transform nonpathogenic cells.

The Griffith experiment served as a foundation for the study of genetic material. Streptococcus pneumoniae was used in research by Frederick Griffith.
Streptococcus pneumoniae bacteria were cultivated by Griffith throughout the experiment, and they displayed two growth patterns. One culture plate had rough colonies (R), while the other contained smooth glossy colonies (S). The difference was caused by the S strain bacteria having a mucous coat, whereas the R strain bacteria did not.
Griffith carried out an experiment by injecting mice with both S and R strains. The person who had the S strain of the infection developed pneumonia and passed away, whereas the person who had the R strain of the infection survived.
Griffith heated the S strain bacteria in the second stage before injecting it into mice, but the mice survived. Then he combined the live and heat-killed R strains. When mice were injected with this mixture, the mice perished. Additionally, in dead mice, he discovered live S strain bacteria.
Griffith came to the conclusion that S strain bacteria had changed R strain bacteria based on his observation. The S strain bacteria were heat-killed, but the R strain gained a "transforming principle" from them that rendered them virulent. He also believed that this transformative principle was genetically encoded.

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