broad-spectrum drugs that disrupt the body's normal flora often cause nephrotoxicity superinfections allergic reactions drug toxicity all of the choices are correct

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A superinfection is a second infection that is brought on by an earlier one and is often caused by a new microbial agent (Virus) that is resistant to the medication being used to treat the previous infection, whether it is exogenous or endogenous.

A cell that has already been infected by one virus might become superinfected when it is subsequently infected by a different strain of that virus or another virus. When compared to narrow spectrum treatments, utilizing broad spectrum medications increases the risk of superinfections. Carbapenem and piperacillin-tazobactam were linked to a substantial incidence of superinfection in several studies. Some implants had to be removed due to the quantity and severity of tissue loss. Broad-spectrum antibiotic use in immunocompetent people carries a significant risk of peri-implant superinfections.

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