The evaluation for neural tube defects should be included in a patient that took carbamazepine throughout the first trimester of pregnancy. This drug is generally used to treat epilepsy.
Carbamazepine is an anticonvulsant drug often used for the treatment of epilepsy and neuropathic pain caused by diabetes.
Carbamazepine has recently been associated with an increased risk of congenital malformations and neurodevelopmental abnormalities during pregnancy.
Specifically, it has been shown that carbamazepine may be associated with defects in the formation of the neural tube during the first trimester of pregnancy.
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